Identification of the Pseudorabies Virus Promoter Required for Latency-Associated Transcript Gene Expression in the Natural Host

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Expression of the pseudorabies virus latency-associated transcript gene during productive infection of cultured cells.

Like other alphaherpesviruses, pseudorabies virus (PrV) exhibits restricted gene expression during latency. These latency-associated transcripts (LATs) are derived from the region located within 0.69 to 0.77 map units of the viral genome. However, the presence of such viral RNAs during a productive infection has not been described. Although several transcripts originating between 0.706 to 0.737...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2000

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.74.14.6333-6338.2000